You are currently viewing 4 Best Practices to Scale-up COVID19 Vaccine Production

4 Best Practices to Scale-up COVID19 Vaccine Production

The process of vaccine production is a continually updating and refreshing technology. The innovative technologies give researchers numerous opportunities to adjust processes and achieve cost-effective scale-up of production. The COVID-19 vaccine rush has shown the world why aligning and optimizing new methods is crucial for companies and organizations.

In today’s time, ‘plug and play’ doesn’t happen in the scientific world and customizing solutions is a critical skill set for the production of vaccines. Customization is inevitable for ensuring that technologies from different sources can work together for enhanced efficiency. At times, this can lead to a conflict of interest and there is always time pressure to fuel it. That being said, here we discuss 4 best practices to smoothly work on vaccine scale-up production with customization in mind.

  • Finding suppliers that offer technical support

Suppliers who offer technical support in labs can provide lab personnel with fresh perspectives on already-established practices. Their technical opinions can help scientists to navigate through optimization challenges by customizing and troubleshooting new technologies for improving yield. Many companies have started to offer services from field application scientists to labs in terms of the machining process and biological aspects.

  • Don’t invest in unnecessary improvements

Technical advancements are undoubtedly needed but not every lab needs the biggest sophisticated scale-up machinery and many labs cannot afford it. It is therefore very important to plot out the needs of the lab. Planning the short-term and long-term objectives can help in budget management to ensure that the technical aspect of the whole process is optimized. Moreover, every service provider should ask these questions: ‘What is the level of the desired scale-up? What time do you envision? What is the current status of the technology and lab infrastructure?’ Every production-based lab should customize the most favorable scenario with their technology provider by going through several alternative strategies and come up with the best one having an optimized load.

  • Not only technology but also biology

Engineers are a driving force for process development but so are biologists, where biological process like vaccine production is concerned. Working with service providers and suppliers that can provide both engineers and life scientists can help ensure that the technology is implemented successfully to work towards the required biological outcome. Just machine development does not optimize the workflow without optimizing conditions for the actual scientific work.

  • Go modular

That’s the new work mode: modular! To ensure short-term cost optimization and technology flexibility, it is important to create a modular scalable production suite. By acknowledging the modular model of scaling up production, researchers allow more adaptability and responsiveness to their lab’s working.

Investing in technologies that allow a modular approach helps researchers to scale up when they need instead of creating a huge supply regardless of the demands. The modular approach can help scientists to avoid the upfront costs of a larger investment and provide flexibility to arrange new products and technologies for up-to-date customizations.

If your lab is working on COVID-19 vaccine production, choose the right partner for procuring your primary cells. KOSHEEKA provides a wide array of quality-characterized primary cells along with the necessary technical expertise to help your research. Contact KOSHEEKA at for more info.

Leave a Reply