Cynomolgus cryopreserved hepatocytes, plateable

Cynomolgus cryopreserved hepatocytes, plateable

CD-1 Schwann cells

Isolated from the ventricles of the adult heart. These cells are qualified for the in vitro research on cardiac diseases as well as for pharmacological studies. The HCM can be cultured for as long as 10 population doublings, and hence are suitable for long term experiments.

CD-1 Pulmonary fibroblasts

CD-1 NK cells

CD-1 Mouse Whole Blood

CD-1 Mouse Serum

CD-1 Mouse Plasma

CD-1 Mouse Lung S9

CD-1 mouse S9 fraction is derived from mouse lung tissue, preserving the physiological relevance necessary for accurate in vitro studies related to lung drug metabolism and pulmonary pharmacology. Primary CD-1 mouse S9 fraction is sourced from mouse lung tissue, and boasts a rich concentration of drug-metabolizing enzymes specific to lung tissues, offering an authentic in vitro platform to explore lung drug metabolism, evaluate the safety of respiratory therapies, and delve into the bioavailability of inhaled drugs. Meticulously purified and quality-controlled, our CD-1 mouse S9 Fraction assures the consistency and reliability necessary for gaining profound insights into lung-specific pharmacology and pulmonary drug delivery.

CD-1 Mouse Lung Microsomes

CD-1 mouse microsomes is derived from mouse lung tissue, preserving the physiological relevance necessary for accurate in vitro studies related to lung drug metabolism and pulmonary pharmacology. CD-1 mouse hepatic microsomes are sourced from human lung tissue, and boasts a rich concentration of drug-metabolizing enzymes specific to metabolic tissues, offering an authentic in vitro platform to explore lung drug metabolism, evaluate the safety of respiratory therapies, and delve into the bioavailability of inhaled drugs. Meticulously purified and quality-controlled, our CD-1 mouse microsomes assures the consistency and reliability necessary for gaining profound insights into lung-specific pharmacology and pulmonary drug delivery.

CD-1 Mouse Lung Cytosol

CD-1 mouse S9 fraction is derived from mouse lung tissue, preserving the physiological relevance necessary for accurate in vitro studies related to lung drug metabolism and pulmonary pharmacology. Lung S9 fraction boasts a rich concentration of drug-metabolizing enzymes specific to pulmonary tissues, offering an authentic in vitro platform to explore lung drug metabolism, evaluate the safety of respiratory therapies, and delve into the bioavailability of inhaled drugs. Meticulously purified and quality-controlled, our CD-1 mouse hepatic S9 fraction assures the consistency and reliability necessary for gaining profound insights into lung-specific pharmacology and pulmonary drug delivery.

CD-1 Mouse Liver S9

CD-1 Mouse Liver Microsomes

CD-1 Mouse Liver Cytosol

CD-1 Mouse Intestine S9

CD-1 Mouse Intestine Microsomes

CD-1 Mouse Intestine Cytosol

CD-1 Mononuclear cells

CD-1 Mesenchymal stem cells

CD-1 Hepatocytes plateable

In drug development projects, there is a significant concern about finding models for drug-to-drug interactions (DDI) with clinical relevance. Plateable CD-1 mouse hepatocytes, specialized primary liver cells, are derived from CD-1 mouse. These cells possess a unique ability to adhere and grow on culture plates or dishes, making them indispensable tools for drug development, toxicology, liver-related studies, and disease modeling.

At Kosheeka, we ensure that these hepatocytes are thoroughly tested for high viability and sustained healthy culture duration. The possess induction qualifications, making them highly valuable for DDI studies. These cells undergo comprehensive characterization for transporter activity and enzyme activity, focusing on major mechanisms involved in drug interactions.

The featured characteristics of these hepatocytes include confluence monolayer, distinct cobblestone appearance, and inducibility of enzyme activity for CYP3A4, CYP2B6, and CYP1A2. We also analyze their basal metabolism for eight CYPs, SULT, UGT, and aldehyde oxidase. Additionally, we pretest these cells for long-term culture, spheroid formation, and compatibility with 96-well plates.

Choose our plateable hepatocytes to enhance the clinical relevance of your drug development projects and ensure accurate predictions of drug interactions for better research outcome.

CD-1 Dermal Fibroblast

CD-1 Dendritic cells

CD-1 Cardiomyocytes

Isolated from the ventricles of the adult heart. These cells are qualified for the in vitro research on cardiac diseases as well as for pharmacological studies. The HCM can be cultured for as long as 10 population doublings, and hence are suitable for long term experiments.

CD-1 Cardiac fibroblasts

Cardiac fibroblasts form the major part of heart tissue. They produce connective tissue which maintains the extracellular matrix of the heart. They are essential in studying proper heart function and physilogy. Research using these cells includes neointimal formation, tissue remodeling, myocardial and vascular repair, toxicology and drug screening, genetic therapy, extracellular repair, growth factors and cytokines.

CD-1 Brain vascular pericytes

Cardiomyocytes

Cardiac fibroblasts

C57 Schwann cells

C57 Pulmonary fibroblasts

C57 NK cells

C57 Mouse Whole Blood

C57 Mouse Skin S9

C57 Mouse Skin Microsomes

C57 Mouse Skin Cytosol

C57 Mouse Serum

C57 Mouse Plasma

C57 Mouse Lung S9

C57 Mouse Lung Microsomes

C57 Mouse Lung Cytosol

C57 Mouse Liver S9

C57 Mouse Liver Microsomes

C57 Mouse Liver Cytosol

C57 Mouse Intestine S9

C57 Mouse Intestine Microsomes

C57 Mouse Intestine Cytosol

C57 Mouse Heart S9

C57 Mouse Heart Microsomes

C57 Mouse Heart Cytosol

C57 Mononuclear cells

C57 Mesenchymal stem cells